When Superman and the rest of the Justice League are kidnapped, Krypto the Super-Dog must convince a rag-tag shelter pack - Ace the hound, PB the potbellied pig, Merton the turtle and Chip the squirrel - to master their own newfound powers and help him rescue the superheroes. Krypto the Super-Dog and Superman are inseparable best friends, sharing the same superpowers and fighting crime side by side in Metropolis. However, Krypto must master his own powers for a rescue mission when Superman is kidnapped.