A fatalistic car crash in Mexico city sets off a chain of events in the lives of three people: a supermodel, a young man wanting to run off with his sister-in-law, and a homeless man. Their lives are catapulted into unforeseen situations instigated by the seemingly inconsequential destiny of a dog. An amateur dog fighter, a supermodel, and a derelict assassin, all separately struggling to find love, find their lives transformed by a devastating car wreck in Mexico City.